A single NLR gene confers resistance to leaf and stripe rust in wheat

A single NLR gene confers resistance to leaf and stripe rust in wheat

Blog Article

Ski de fond - Homme - Bottes - Combi Abstract Nucleotide-binding leucine-rich repeat (NLR) disease resistance genes typically confer resistance against races of a single pathogen.Here, we report that Yr87/Lr85, an NLR gene from Aegilops sharonensis and Aegilops longissima, confers resistance against both P.striiformis tritici (Pst) and Puccinia triticina (Pt) that cause stripe and leaf rust, respectively.Yr87/Lr85 confers resistance against Pst and Pt in wheat introgression as well as transgenic lines.

Comparative analysis of Yr87/Lr85 and the cloned Triticeae NLR disease resistance genes shows that Yr87/Lr85 contains two distinct LRR domains and that the gene is only found in Ae.sharonensis and Ae.longissima.Allele mining and phylogenetic analysis indicate multiple events of Yr87/Lr85 gene flow between the two species Leveler and presence/absence variation explaining the majority of resistance to wheat leaf rust in both species.

The confinement of Yr87/Lr85 to Ae.sharonensis and Ae.longissima and the resistance in wheat against Pst and Pt highlight the potential of these species as valuable sources of disease resistance genes for wheat improvement.